KRAS-driven lung cancers are difficult to treat due to rapid resistance and tumor heterogeneity. In this webinar, Dr. Mukesh Nyati (University of Michigan) and Marco Corbo (Signios Bio) discuss how spatial transcriptomics was used to analyze preclinical lung tumor models and uncover the biological changes that drive resistance.
You’ll hear how spatial gene expression profiling revealed:
-
Regional EGFR protein degradation post-treatment
-
Localized immune suppression in the tumor microenvironment
-
Distinct metabolic signatures missed by bulk or single-cell approaches
Whether you’re exploring spatial transcriptomics or already integrating it into your workflows, this session offers practical insights into its role in oncology research.
Speakers
Dr. Mukesh Nyati, University of Michigan
Marco Corbo, PhD., Signios Bio
Register to watch recording
Why Choose Signios Bio?
With Signios, you get more than just sequencing. You gain a partner dedicated to supporting your research through every step of the process, from precise sample preparation to comprehensive bioinformatics analysis. Our team of expert scientists and cutting-edge technology will help you uncover new insights and drive your research forward.
"Always very quick responses, wonderful turnaround times and exemplary quality of service. Data is always great, and any issues are always resolved. The price is competitive, stable and reliable."
Cassie Pond
The Feinstein Institutes for Medical Research